XADAGO  Exercise

The support you need—when you need it

The XADAGO Together Program is your resource for additional PD information, educational materials, savings support, and more.


The XADAGO Prescription Savings Program is here to help provide cost savings to eligible patients* - so you can get the prescription you need exactly as prescribed by your healthcare provider.

Pay as little as $25*
(save up to $125) on your XADAGO prescription each month

If you’ve recently been prescribed XADAGO

Simply take your prescription for XADAGO to a participating pharmacy and the savings will be automatically applied to your co-pay.

For more information about the XADAGO Prescription Savings Program, please review the Terms and Conditions.

Find a participating pharmacy near you

Automatic co-pay savings at over 67,000 pharmacies including many well-known chains, such as:

  • Costco
  • CVS Health
  • Good Neighbor
  • Kmart
  • Kroger
  • Medicine Shoppe
  • Publix
  • RiteAid
  • Safeway/Albertsons
  • Sam's Club
  • ShopRite
  • Target
  • Walgreens
  • Walmart
  • Winn-Dixie
  • To find a participating pharmacy near you, click Find Participating Pharmacies.

    If your preferred pharmacy is not listed, please try searching the Additional Pharmacy Options.

    For more information about the XADAGO Prescription Savings Program, please review the Terms and Conditions.

    *Patients whose prescriptions will be paid for in part or in whole by Medicare, Medicaid, or any similar federal or state healthcare program, are not eligible for savings or rebates according to federal and state law. Patients must visit a participating pharmacy for savings or rebates on their XADAGO prescriptions.

    The actual savings on out-of-pocket costs for XADAGO will vary according to refill quantity, personal healthcare insurance coverage, and adherence to FDA dosing guidelines. Please review the XADAGO Prescription Savings Program Terms and Conditions to learn more.

    If you cannot afford your medication there are programs that may be able to help.
    Call 1-888-4XADAGO, Option 3 to learn more.


    We're here to help you understand and manage your care—or the care of your loved one—with once-daily XADAGO.

    The XADAGO Together Program is your resource for:

    • XADAGO and PD information
    • XADAGO refill reminders
    • Savings on your XADAGO prescriptions**
    • Tools to help you talk to your healthcare provider about XADAGO
    • Lifestyle tips for patients with PD and their care partners

    **Eligibility restrictions may apply.

    Sign up today to take advantage of all that XADAGO Together offers.

    Are you currently taking XADAGO - or would you like to receive more information about XADAGO? Sign up today!

    I am interested in being enrolled in the XADAGO TOGETHER program for support and savings
    I would like to sign up to receive more information to talk to my healthcare provider about XADAGO

    Frequently Asked Questions ABOUT XADAGO1

    These questions are for people considering XADAGO and patients prescribed XADAGO.
    Do not replace talking with your healthcare provider with these FAQs—and always follow your healthcare provider’s instructions.

    XADAGO (safinamide) is a type of prescription medicine known as a monoamine oxidase type B (MAO-B) inhibitor used with levodopa/carbidopa to treat individuals with Parkinson’s disease (PD) who are having off episodes. It is not known if XADAGO is effective to treat PD when taken as a single medicine (monotherapy). It is not known if XADAGO is safe and effective in children.
    The recommended starting dose of XADAGO is 50 mg once daily. After 2 weeks, your healthcare provider may decide to increase your dose to 100 mg once daily, if necessary. It is recommended to take XADAGO at the same time each day. Do not start or stop taking XADAGO without talking to your healthcare provider first.
    The most common side effects seen with XADAGO are uncontrolled movements (dyskinesia), falls, nausea, and trouble sleeping or falling asleep (insomnia).
    No, you do not have to change your diet. Restriction of foods and beverages is usually not required when treated with the recommended doses of XADAGO.
    Please talk with your healthcare provider about any changes to your PD medications. XADAGO is intended to be used with levodopa/carbidopa (monotherapy) medications to treat Parkinson’s disease. It is not known if XADAGO is effective to treat PD when taken as a single medicine.
    Do not use XADAGO if you are allergic to XADAGO (safinamide), as this can cause swelling of the tongue and mouth and trouble breathing. You should not take XADAGO if you have severe liver disease. Please talk to your healthcare provider if you have concerns about taking XADAGO.
    The combination of MAO-B inhibitors like XADAGO and antidepressants has resulted in a serious and sometimes fatal condition called serotonin syndrome.

    Do not take XADAGO with opioid medications including meperidine, tramadol, methadone, or propoxyphene, as this could result in serious, sometimes fatal, reactions.

    Also, do not take XADAGO with amphetamine, cyclobenzaprine, methylphenidate, or St. John’s wort. Taking these drugs together can also result in serotonin syndrome, which could be fatal.

    Do not use XADAGO with dextromethorphan. The combination of MAO inhibitors and dextromethorphan has been reported to cause episodes of psychosis or abnormal behavior.
    If a dose of once-daily XADAGO is missed, the next dose should be taken at the same time the next day.
    XADAGO should be stored at room temperature, between 68 and 77 degrees, but also allows for temperatures as low as 59 degrees, and as high as 86 degrees.
    Call your healthcare provider for medical advice about side effects. You may report side effects by contacting US WorldMeds at 1-888-492-3246 (1-888-4XADAGO). You may also report suspected adverse reactions to the FDA at 1-800-FDA-1088 or www.fda.gov/medwatch.

    XADAGO patient brochure

    If your healthcare provider has prescribed XADAGO, or you are considering talking to your healthcare provider about it, you may find it helpful to read this.

    We’ve created the following downloadable brochure to provide you with an overview of PD symptoms and treatment with XADAGO.

    This comprehensive brochure covers how XADAGO works, clinical trial results, safety information, and more.

    Consider sharing this brochure with your healthcare provider—and we encourage you to bring it with you to your next appoinment.

    1. XADAGO Full Prescribing Information. May 2017.