If any of your PD patients are experiencing the following, he or she may benefit from once-daily XADAGO.
These profiles represent patients who may be appropriate for treatment with XADAGO.
First noticed right-hand tremor at age 55 and was diagnosed with Parkinson's disease (PD) a year later. He was initially started on a dopamine agonist but did not tolerate due to side effects—sometimes he would feel dizzy or more tired. He tolerated the change to carbidopa/levodopa 25/100 mg three times a day with good response.
About 1 year after starting carbidopa/levodopa, patient notes increased slowness, rigidity, and tremor with the current dose of carbidopa/levodopa. The symptoms are interfering with his work around the shop.
Diagnosed with PD 4 years ago, 62-year-old female had improved motor function with carbidopa/levodopa (25 mg/100 mg) three times a day and pramipexole ER 2.25 mg.
Now she is experiencing her carbidopa/levodopa dose wearing, off sooner than previously. About 30-45 minutes before each dose, she notes increased tremor and balance difficulty. She is unable to increase her pramipexole due to lower-extremity edema at higher doses. The off time impairs her work as a part-time accountant.